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中国科学基金

自然科学进展

Progress in Natural Science



Recent Progress of Somatic Cell Nuclear Transfer in Pigs
Xu Xiaoming,Dou Zhongying
Northwest A&F University, Shaanxi Branch of National Stem Cell Engineering and Technology, Yangling 712100
Abstract:  Research in the field of somatic cell nuclear transfer (SCNT) and transgenic cloning in pigs has become a global hotspot,because porcine organs probably can be the first source of donor organs for human xenotransplantation. In recent years, though great progress has been made in porcine SCNT, the efficiency of nuclear transfer remains very low (<1%). Thus, it is necessary to improve the procedure of nuclear transfer and to investigate some basic problems further. Recent progress and the related problems of SCNT in pigs are reviewed and analyzed so as to offer some beneficial illumination to researchers.
Keywords:  nuclear transfer, cloning, transgene, pig
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